| ￥3300 | |
| Z03806-100 | |
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| Species | Human | ||||||
| Protein Construction |
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| Purity |
> 95% as determined by Bis-Tris PAGE > 95% as determined by HPLC |
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| Endotoxin Level | Less than 1EU per μg by the LAL method. | ||||||
| Biological Activity | Immobilized Her2, Avi & His, Human (Cat.No.: Z03806) at 0.5 μg/ml can bind Anti-Her2 Antibody. | ||||||
| Expression System | HEK293 | ||||||
| Theoretical Molecular Weight | 72.3 kDa | ||||||
| Apparent Molecular Weight | Due to glycosylation, the protein migrates to 80-100 kDa based on Bis-Tris PAGE result. | ||||||
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. | ||||||
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. | ||||||
| Storage & Stability | Upon receiving, the lyophilized product remains stable up to 6 months at -20 °C or below as supplied from date of receipt.-80°C for 3 months after reconstitution.Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Her2, Avi & His, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »
The purity of Her2, Avi & His, Human is greater than 95% as determined by SEC-HPLC. »
Immobilized Her2, Avi & His, Human at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-HER2 Antibody, hFc Tag with the EC50 of 7.4 ng/ml determined by ELISA. »
| Target Background | ErbB2, also known as Neu and Her2, is a type I membrane glycoprotein belonging to the ErbB family of tyrosine kinase receptors. It serves as a receptor for the epidermal growth factor (EGF) family of growth factors. Upon activation, ERBB2 triggers the MEMO1-RHOA-DIAPH1 signaling pathway, leading to the phosphorylation and inhibition of GSK3B at the cell membrane. |
| Synonyms | EGFR2; ErbB2; HER2; HER-2; TKR1; ERBB2; |
For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.
