目录产品 » PD-1 Antibody (2E5), mAb, Mouse
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PD-1 (2E5), mAb, Mouse

Programmed Cell Death Protein 1 (PD-1), is cell surface receptor expressing on T cells and pro-B cells. The binding of PD-1 to its two ligands, PD-L1 and PD-L2, could result in down-regulation of the immune system by inhibiting the T-cell activation process. Thus, PD-1 is an important immune checkpoint and a popular target for therapeutic antibodies against many cancers.
询价
V02201-0.1

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产品概述
Specificity Human PD-1
Clone ID 2E5
Isotype IgG1
Subclass IgG1
Host Species Mouse
Antigen Species Human
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产品属性
Conjugation Unconjugated
Production Cultured in vitro under conditions free from animal-derived components
Purification Protein A/G affinity column
Concentration ≥ 2mg/ml
Formulation 50 mM Na-citrate, 150 mM NaCl, pH 7.0, containing 0.03% ProClin 300.
Storage For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.
Note GenScript can customize this product per customer's request including product size, buffer components, etc.
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应用指导
IHC
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图例
PD-1 (2E5), MAb, Mouse

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PD-1 (2E5), MAb, Mouse

Immunohistochemistry analysis of human Lymph node slide (Paraffin embedded) using PD-1 Antibody, mAb, Mouse (GenScript, Cat. V02201) »

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技术背景
Target Background Programmed Cell Death Protein 1 (PD-1), is cell surface receptor expressing on T cells and pro-B cells. The binding of PD-1 to its two ligands, PD-L1 and PD-L2, could result in down-regulation of the immune system by inhibiting the T-cell activation process. Thus, PD-1 is an important immune checkpoint and a popular target for therapeutic antibodies against many cancers.
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有限使用许可与使用限制
有限使用许可与使用限制 This Product is provided under a limited, non-exclusive, non-transferable, and non-sublicensable end-user license strictly limited to the permitted uses set forth in GenScript’s official documentation, quotations, or written agreements. Any use beyond such scope requires GenScript’s prior written authorization or license.
Except as expressly authorized in writing by GenScript, Customer shall not, and shall not permit, procure, enable, or assist any third party to: (a) commercialize or otherwise exploit the Product, including by reselling, distributing, transferring, sublicensing, or otherwise making the Product (including any product incorporating the Product) available to any third party; (b) copy, reproduce, clone, reverse clone, sequence, analyze, characterize, deconstruct, reconstruct, reverse engineer, or otherwise attempt to discover the composition, sequence, structure, binding characteristics, epitope recognition characteristics, or other proprietary features of the Product; (c) modify, derivatize, humanize, optimize, mutate, design around, or generate any variants, derivatives, fragments, substitutes, or functional equivalents of the Product; or (d) use the Product, any information derived therefrom, or any computational, AI-enabled, or sequence-based design method to develop, manufacture, offer for sale, sell, or commercialize any product or service competitive with the Product or GenScript’s products or services.
All intellectual property rights and all rights not expressly granted herein are reserved by GenScript. No rights are granted by implication, estoppel, or otherwise.
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For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.