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Jagged-1 (188-204)

This peptide is a fragment of the JAG-1 protein. JAG-1 is Notch ligand, a peptide that is the most conspicuously expressed ligand in skin. JAG-1 induces epidermal maturation. Exposing submerged keratinocytes monolayers to JAG-1 with elevated calcium concentration produces stratification with loricrin expression and NF-αB activation.
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RP20331

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产品概述
Description This peptide is a fragment of the JAG-1 protein. JAG-1 is Notch ligand, a peptide that is the most conspicuously expressed ligand in skin. JAG-1 induces epidermal maturation. Exposing submerged keratinocytes monolayers to JAG-1 with elevated calcium concentration produces stratification with loricrin expression and NF-αB activation.
Sequence
{Cys}{Asp}{Asp}{Tyr}{Tyr}{Tyr}{Gly}{Phe}{Gly}{Cys}{Asn}{Lys}
{Phe}{Cys}{Arg}{Pro}{Arg}
Sequence Shortening CDDYYYGFGCNKFCRPR
Molecular Formula C93H124N25O26S3
Molecular Weight 2107.4
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产品属性
Purity > 95%
Solubility Soluble in dimethyl sulfoxide(Analytical grade) under 1mg/ml
Form Lyophilized
Storage Store at -20°C.
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相关文献
Jardé T, et al. Mesenchymal Niche-Derived Neuregulin-1 Drives Intestinal Stem Cell Proliferation and Regeneration of Damaged Epithelium. Cell Stem Cell. (2020-10)