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Bombesin

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Bombesin is a 14 amino acid peptide originally isolated from the skin of a frog. Bombesin has two known homologues in mammals called neuromedin B and gastrin releasing peptide. Bombesin works on the gastrointestinal tract neuroendocrine hormone and bombesin stimulates gastrin release from G cells. Bombesin activates three different G-protein coupled receptors known as BBR1 2 and 3. Bombesin also activates these receptors in the brain. Together with cholecystokinin bombesin is the second major source of negative feedback signals that stop eating behavior.
RP11157
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Description Bombesin is a 14 amino acid peptide originally isolated from the skin of a frog. Bombesin has two known homologues in mammals called neuromedin B and gastrin releasing peptide. Bombesin works on the gastrointestinal tract neuroendocrine hormone and bombesin stimulates gastrin release from G cells. Bombesin activates three different G-protein coupled receptors known as BBR1 2 and 3. Bombesin also activates these receptors in the brain. Together with cholecystokinin bombesin is the second major source of negative feedback signals that stop eating behavior.
Cas No 31362-50-2
Sequence
{pGLU}{GLN}{ARG}{LEU}{GLY}{ASN}{GLN}{TRP}{ALA}{VAL}{GLY}{HIS
}{LEU}{MET}
Sequence Shortening {pGLU}QRLGNQWAVGHLM
Molecular Formula C71H110N24O18S1
C Terminal NH2
Molecular Weight 1619.9

Purity > 95%
Solubility 20 mg/ml CH3COOH 0.05 M clear, colorless
Form Lyophilized
Storage Store at -20°C

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