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γ-1-Melanocyte Stimulating Hormone (MSH), amide

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Gamma-MSH (Melanocyte Stimulating Hormone), a putative hormone in the N-terminal region of the ACTH/beta- endorphin (beta-EP) precursor protein, was studied by RIA with an antiserum against gamma 3-MSH in ACTH-producing mouse pituitary tumor cells, AtT-20/D16v. Gamma-MSH peptides have low intrinsic melanotropic activity in mammalian melanoma cells; the specific pigmentary responses appear to be affected by the structure of the C-terminal portion.
RP10650
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Synonyms

γ-1-MSH, amide;γ1-MSH; g-1-MSH; g1-MSH; gamma-1-MSH; gamma1-MSHγ-1-Melanocyte Stimulating Hormone; γ1-Melanocyte Stimulating Hormone; g-1-Melanocyte Stimulating Hormone; g1-Melanocyte Stimulating Hormone; gamma-1-Melanocyte Stimulating Hormone; gamma1-Melanocyte Stimulating Hormone

Note

Gamma-1-MSH is derived from ACTH 1-13. Gamma-1-MSH is a hormone that stimulates melanogenesis and facilitates learning and memory. Gamma-1-MSH can affect inflammatory and immune responses and peripheral nerve regeneration.

Sequence
{TYR}{VAL}{MET}{GLY}{HIS}{PHE}{ARG}{TRP}{ASP}{ARG}{PHE}-NH2
Sequence Shortening YVMGHFRWDRF-NH2
Molecular Formula C72H97N21O14S1
C Terminal NH2
Molecular Weight 1512.9

Purity > 95%
Storage Store the peptide at -20°C. Keep container tightly closed.

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