β-Melanocyte Stimulating Hormone (MSH), human

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Alpha-MSH (melanocyte stimulating hormone) has generally been assumed to be the endogenous ligand acting at the melanocortin-4 receptor (MC4-R), activation of which in the hypothalamus leads to reduced feeding. However, beta-MSH is also capable of activating MC4-R and inhibiting feeding. The researchers found that obese children are more likely to carry a rare variant of so-called beta-melanocyte-stimulating hormone (beta-MSH) than children of normal weight.

产品编号	RP10648
规格	定制报价

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产品概述

Synonyms	beta melanocyte stimulating hormoneβ-MSH, human
Description	Alpha-MSH (melanocyte stimulating hormone) has generally been assumed to be the endogenous ligand acting at the melanocortin-4 receptor (MC4-R), activation of which in the hypothalamus leads to reduced feeding. However, beta-MSH is also capable of activating MC4-R and inhibiting feeding. The researchers found that obese children are more likely to carry a rare variant of so-called beta-melanocyte-stimulating hormone (beta-MSH) than children of normal weight.
Cas No	17908-57-5
Sequence	{ALA}{GLU}{LYS}{LYS}{ASP}{GLU}{GLY}{PRO}{TYR}{ARG}{MET}{GLU} {HIS}{PHE}{ARG}{TRP}{GLY}{SER}{PRO}{PRO}{LYS}{ASP}
Sequence Shortening	AEKKDEGPYRMEHFRWGSPPKD
Molecular Formula	C₁₁₈H₁₇₄N₃₄O₃₅S₁
Molecular Weight	2661.0