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PACAP (1-38), human, ovine, rat

PACAP (1-38), a novel neuropeptide isolated from the bovine hypothalamus is more active than vasoactive intestinal peptide (VIP) in stimulating adenylate cyclase (EC50=7 nM). PACAP 1-38 (10-9 M) increased substance P (SP), gastrin releasing peptide (GRP), and VIP release. PACAP 1-38 (10-8 M) inhibited gastrin secretion and stimulated somatostatin secretion and motility dose-dependently.
￥1400
RP10335

产品概述
Description PACAP (1-38), a novel neuropeptide isolated from the bovine hypothalamus is more active than vasoactive intestinal peptide (VIP) in stimulating adenylate cyclase (EC50=7 nM). PACAP 1-38 (10-9 M) increased substance P (SP), gastrin releasing peptide (GRP), and VIP release. PACAP 1-38 (10-8 M) inhibited gastrin secretion and stimulated somatostatin secretion and motility dose-dependently.
Cas No 137061-48-4
Sequence
{HIS}{SER}{ASP}{GLY}{ILE}{PHE}{THR}{ASP}{SER}{TYR}{SER}{ARG}
{TYR}{ARG}{LYS}{GLN}{MET}{ALA}{VAL}{LYS}{LYS}{TYR}{LEU}{ALA}
{ALA}{VAL}{LEU}{GLY}{LYS}{ARG}{TYR}{LYS}{GLN}{ARG}{VAL}{LYS}
{ASN}{LYS}
Sequence Shortening HSDGIFTDSYSRYRKQMAVKKYLAAVLGKRYKQRVKNK
Molecular Formula C203H331N63O53S1
C Terminal Amidation
Molecular Weight 4534.26
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产品属性
Purity > 95%
Solubility Soluble in Ultrapure water under 1mg/ml
Form Lyophilized
Storage Store the peptide at -20°C.
Note PACAP stimulates adenylate cyclase in rat anterior pituitary cells.
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