目录产品 » Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat
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Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat

Myelin oligodendrocyte glycoprotein (MOG) is found exclusively in the CNS, where it is localized on the surface of myelin and oligodendrocyte cytoplasmic membranes and has been implicated as an important autoantigen in multiple sclerosis (MS). This peptide induces severe chronic experimental autoimmune encephalomyelitis in transgenic mice.
￥1400
RP10245

产品概述
Synonyms MOG(35-55)
Description Myelin oligodendrocyte glycoprotein (MOG) is found exclusively in the CNS, where it is localized on the surface of myelin and oligodendrocyte cytoplasmic membranes and has been implicated as an important autoantigen in multiple sclerosis (MS). This peptide induces severe chronic experimental autoimmune encephalomyelitis in transgenic mice.
Cas No 163913-87-9
Sequence
{MET}{GLU}{VAL}{GLY}{TRP}{TYR}{ARG}{SER}{PRO}{PHE}{SER}{ARG}
{VAL}{VAL}{HIS}{LEU}{TYR}{ARG}{ASN}{GLY}{LYS}
Sequence Shortening MEVGWYRSPFSRVVHLYRNGK
Molecular Formula C118H177N35O29S1
Molecular Weight 2581.98
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产品属性
Purity 95%
Solubility Soluble in Ultrapure water under 1mg/ml
Form Lyophilized
Storage Store at -20°C.
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相关文献
Erwan Baudron, et al. Intestinal MAdCAM-1 imaging as biomarker for prognostic in murine models of multiple sclerosis. Brain Behav Immun. (2024-04)
Keller CW, et al. CYBB/NOX2 in conventional DCs controls T cell encephalitogenicity during neuroinflammation. Autophagy. (2020-05)
Angiari S, et al. Pharmacological Activation of Pyruvate Kinase M2 Inhibits CD4+ T Cell Pathogenicity and Suppresses Autoimmunity. Cell Metab. (2020)
Keller Christian W, et al. ATG-dependent phagocytosis in dendritic cells drives myelin-specific CD4 T cell pathogenicity during CNS inflammation. Proc. Natl. Acad. Sci. U.S.A. (2017)
M Zhuravleva, et al. Effect of GDNF on Morphology, Proliferation, and Phagocytic Activity of Rat Neonatal Cortex Isolated Microglia. Bionanoscience. (2016-08)
Margarita Zhuravleva & Albert Rizvanov1 & Yana Mukhamedshina, et al. Effect of GDNF on Morphology, Proliferation, and Phagocytic Activity of Rat Neonatal Cortex Isolated Microglia. BioNanoSci. (2016-01)