PE6c

PE6C focuses on enhancing the performance of prime editing in transgenic rice plants. This specific variant of the prime editing technology is tailored to address the challenges of genetic improvement in crops, contributing to enhanced editing precision and efficiency in agricultural applications. The effectiveness of PE6c stems from its design improvements that enable it to facilitate targeted insertions and modifications in plant genomes.

价格	￥1050 在线订购包邮(港澳台除外)
产品编号	RC00007-30
规格	30 µg (3mg/ml) 100 μg(10mg/ml) 500 μg(10mg/ml) 5 mg (10mg/ml) 大单询价
数量
参考货期


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产品概述应用指导产品属性质控参数图例技术背景

产品概述

Description

应用指导

single guide RNA (sgRNA) dependent single-stranded DNA cleavage

产品属性

Expression System	Recombinant Cas9-based fusion with three NLS expressed by E.coli
Species	S. pyogenes
PAM	NGG
Tag	C-His tag
Molecular Weight	226.54KDa
Storage & Stability	PE6C is supplied with storage buffer (50 mM Tris, 300 mM NaCl, 0.1 mM EDTA, 1 mM DTT, 50% Glycerol pH7.5, at 25°C) and recommended to be stored at -80°C.

质控参数

Purity	≥90% by SDS-PAGE, 92% by SEC-HPLC
Residual DNase	Non-specific DNase activity
Endotoxin Level	Control <10EU/mg

图例

技术背景

References

David R Liu, et al. “Phage-assisted evolution and protein engineering yield compact, efficient prime editors”. Cell. 2023 Aug 31;186(18):3983-4002.e26.