The thyrotropin receptor (TSHR) is the major autoantigen in autoimmune hyperthyroidism. TSHR autoantibodies, acting as TSHR agonists (TRAb), are responsible for Graves’ disease. Measurement of TRAb is important for therapeutic and prognostic purposes. |
GenScript can customize this product per customer's request including product size, buffer components, etc.
Subclass | IgG1 |
Conjugation |
Unconjugated |
Antigen Species | Human |
Production | Cultured in vitro under conditions free from animal-derived components |
Purification | Protein A/G affinity column |
Formulation | 50 mM Na-citrate, 150 mM NaCl, pH 7.0, containing 0.03% Proclin 300 |
Clone ID | M22HC |
Storage | For up to three months at 2-8°C or for up to three years at -25°C~-15°C. Avoid repeated freezing and thawing. |
ELISA |
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Target Background | The thyrotropin receptor (TSHR) is the major autoantigen in autoimmune hyperthyroidism. TSHR autoantibodies, acting as TSHR agonists (TRAb), are responsible for Graves’ disease. Measurement of TRAb is important for therapeutic and prognostic purposes. |