GMP Anti-Human CD28 Antibody (F105), mAb, Mouse
This product is specific for Human CD28
| 询价 | |
| GMPA02213 | |
|
|
|
|
|
|
|
|
|
| 询价 | |
| GMPA02213 | |
|
|
|
|
|
|
|
|
|
| Specificity | This product is specific for Human CD28 |
| Host Species | Mouse |
| Immunogen | Recombinant Human CD28 |
| Conjugate | Unconjugated |
| ex vivo cell culture process; Flow cytometry |
| Form | Liquid |
| Storage Buffer | Supplied in 10 mM Sodium Citrate, 150 mM NaCl, pH 6.5. |
| Concentration | 5 mg/ml |
| Storage Instructions | The product remains stable at -70 ± 10 °C. Avoid repeated freeze-thaw cycles. Please refer to the COA for specific expiry date. |
| Isotype | Mouse IgG1κ |
| Clonality | Monoclonal |
| Clone ID | F105 |
Jurkat/IL-2-Luc Promoter cells were co-stimulated with a serial of concentrations of GMP Anti-Human CD28 Antibody (F105), mAb, Mouse (Cat. No. GMPA02213) and GMP Anti-Human CD3 Antibody (OKT3), mAb, Mouse (Cat. No. GMPA02199) for 6 h. Receptor-mediated signaling induced luminescence via activation of the IL-2 pathway. »
Accelerated stability test of GMP Anti-Human CD28 Antibody (F105), mAb, Mouse (Cat. No. GMPA02213) at 25 ℃ showed that this product is stable at 25 ℃ for 30 days and maintained high purity and potency.
Freeze-thaw cycle stability test of GMP Anti-Human CD28 Antibody (F105), mAb, Mouse (Cat. No. GMPA02213) showed that this product is stable for 5 times of freeze-thaw cycles and maintained high purity and potency. »
| 外观 | Clear, colorless liquid |
| pH | 6.5 ± 0.5 |
| Concentration | 5.0 ± 0.5 mg/ml tested by A280 nm |
| Purity | ≥ 95.0% as analyzed by SEC-HPLC |
| Sequence | The coverage of the light chain and heavy chain sequence was 100% consistent with the theoretical amino acid sequence by mass spectrometry (MS) |
| Residual HCP | ≤ 100.0 ng/mg by ELISA method |
| Residual HCD | ≤ 10.0 pg/mg by quantitative PCR method |
| Residual Protein A | ≤ 10.0 ng/mg by ELISA method |
| Endotoxin Level | < 0.1 EU/mg by gel clotting method |
| Sterility | No growth |
| Reactivity | Qualified |
| Target Background |
CD28 (Cluster of
Differentiation 28) is one of the proteins expressed on T cells that provide
co-stimulatory signals required for T cell activation and survival. It plays an
important role in cell proliferation and cytokine production and promotion of
T-cell survival. It also enhances the production of IL-4 and IL-10 in T cells
in conjunction with TCR/CD3 ligation and CD40L co-stimulation. |
For laboratory
research and ex vivo cell isolation
and culture applications. Direct human use, including taking orally and
injection and clinical use are forbidden.
