目录产品 » p-FGFR3 (Y642) Antibody, mAb, Rabbit
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p-FGFR3 (Y642) Antibody, mAb, Rabbit

Tyrosine-protein kinase that acts as a cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation and apoptosis. Plays an essential role in the regulation of chondrocyte differentiation, proliferation and apoptosis, and is required for normal skeleton development. Regulates both osteogenesis and postnatal bone mineralization by osteoblasts.
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A05387-50

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产品概述
Specificity This product is specific to p-FGFR3 (Y642)
Host Species Rabbit
Immunogen A synthesized peptide derived from human FGFR3 around the phosphorylation site of Y642
Species Reactivity Human; Mouse
Conjugate Unconjugated
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应用指导
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Application Recommended Usage
Western Blot 1:1000-1:2000
Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50-1:200
Immunoprecipitation (IP) 1:20-1:50
Flow Cytometry 1:20-1:100
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产品属性
Form Liquid
Storage Buffer Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Instructions Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.
Purification Affinity-chromatography
Isotype Rabbit IgG
Clonality Monoclonal
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图例
P-FGFR3 (Y642) Antibody, MAb, Rabbit

Western blot analysis of Phospho-FGFR3 (Y724) expression in (1) MCF7 treated with pervanadate cell lysate; (2) untreated. »

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技术背景
Target Background Tyrosine-protein kinase that acts as a cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation and apoptosis. Plays an essential role in the regulation of chondrocyte differentiation, proliferation and apoptosis, and is required for normal skeleton development. Regulates both osteogenesis and postnatal bone mineralization by osteoblasts.
Synonyms ACH; CD333; CEK2; FGFR3; Fibroblast growth factor receptor 3; HSFGFR3EX; Hydroxyaryl protein kinase; JTK4; Tyrosine kinase JTK 4;
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.