目录产品 » Collagen III alpha 1 Antibody, mAb, Rabbit
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Collagen III alpha 1 Antibody, mAb, Rabbit

Collagen type III occurs in most soft connective tissues along with type I collagen. Involved in regulation of cortical development. Is the major ligand of ADGRG1 in the developing brain and binding to ADGRG1 inhibits neuronal migration and activates the RhoA pathway by coupling ADGRG1 to GNA13 and possibly GNA12.
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A05353-50

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产品概述
Specificity This product is specific to Collagen III alpha 1
Host Species Rabbit
Immunogen A synthesized peptide derived from human Collagen III alpha 1
Species Reactivity Human; Mouse; Rat
Conjugate Unconjugated
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应用指导
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Application Recommended Usage
Western Blot 1:1000-1:2000
Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50-1:200
Immunoprecipitation (IP) 1:20-1:50
Flow Cytometry 1:20-1:100
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产品属性
Form Liquid
Storage Buffer Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Instructions Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.
Purification Affinity-chromatography
Isotype Rabbit IgG
Clonality Monoclonal
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图例
Collagen III Alpha 1 Antibody, MAb, Rabbit

Western blot analysis of Collagen III expression in (1) A431 cell lysate; (2) MCF7 cell lysate. »

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技术背景
Target Background Collagen type III occurs in most soft connective tissues along with type I collagen. Involved in regulation of cortical development. Is the major ligand of ADGRG1 in the developing brain and binding to ADGRG1 inhibits neuronal migration and activates the RhoA pathway by coupling ADGRG1 to GNA13 and possibly GNA12.
Synonyms Alpha 1 type III collagen; COL3A1; Collagen III alpha 1 chain precursor; Collagen type III alpha ; EDS4A; Fetal collagen; Type III collagen;
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.