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PLAP Antibody, mAb, Rabbit

Plays a role in protein ubiquitination, sorting and degradation through its association with VCP.Involved in ubiquitin-mediated membrane proteins trafficking to late endosomes in an ESCRT-dependent manner, and hence plays a role in synaptic vesicle recycling.May play a role in macroautophagy, regulating for instance the clearance of damaged lysosomes.
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A05232-50

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产品概述
Specificity This product is specific to PLAP
Host Species Rabbit
Immunogen A synthesized peptide derived from human PLAP
Species Reactivity Human
Conjugate Unconjugated
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应用指导
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Application Recommended Usage
Western Blot 1:1000-1:2000
Immunohistochemistry (IHC) 1:100-1:200
Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50-1:200
Immunohistochemistry Frozen (IHF) 1:50-1:200
Immunoprecipitation (IP) 1:20-1:50
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产品属性
Form Liquid
Storage Buffer Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Instructions Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.
Purification Affinity-chromatography
Isotype Rabbit IgG
Clonality Monoclonal
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图例
PLAP Antibody, MAb, Rabbit

Western blot analysis of PLAP expression in MCF7 cell lysate. »

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技术背景
Target Background Plays a role in protein ubiquitination, sorting and degradation through its association with VCP.Involved in ubiquitin-mediated membrane proteins trafficking to late endosomes in an ESCRT-dependent manner, and hence plays a role in synaptic vesicle recycling.May play a role in macroautophagy, regulating for instance the clearance of damaged lysosomes.
Synonyms Glycerophosphatase; PLA2P; Plaa; PLAP;
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.