Specificity | This product is specific to p-Chk2 (S33/S35) |
Host Species | Rabbit |
Immunogen | A synthesized peptide derived from human Chk2 around the phosphorylation site of S33/S35 |
Species Reactivity | Human |
Conjugate | Unconjugated |
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product. | |||||
|
Form | Liquid |
Storage Buffer | Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
Storage Instructions | Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed. |
Purification | Affinity-chromatography |
Isotype | Rabbit IgG |
Clonality | Monoclonal |
Target Background | Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest, activation of DNA repair and apoptosis in response to the presence of DNA double-strand breaks. |
Synonyms | Cds1; Checkpoint kinase 2; Chek2; hCds1; LFS2; RAD53; Serine/threonine protein kinase Chk2; |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.