目录产品 » p-Focal adhesion kinase 1 (Y576/Y577) Antibody, mAb, Rabbit
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p-Focal adhesion kinase 1 (Y576/Y577) Antibody, mAb, Rabbit

Non-receptor protein-tyrosine kinase that plays an essential role in regulating cell migration, adhesion, spreading, reorganization of the actin cytoskeleton, formation and disassembly of focal adhesions and cell protrusions, cell cycle progression, cell proliferation and apoptosis. Required for early embryonic development and placenta development. Required for embryonic angiogenesis, normal cardiomyocyte migration and proliferation, and normal heart development.
¥1200
A05093

Specificity This product is specific to p-Focal adhesion kinase 1 (Y576/Y577)
Host Species Rabbit
Immunogen A synthesized peptide derived from human Focal adhesion kinase 1 around the phosphorylation site of Y576/Y577
Species Reactivity Human; Mouse
Conjugate Unconjugated
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Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Application Recommended Usage
Western Blot 1:1000-1:2000
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Form Liquid
Storage Buffer Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Instructions Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.
Purification Affinity-chromatography
Isotype Rabbit IgG
Clonality Monoclonal
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Target Background Non-receptor protein-tyrosine kinase that plays an essential role in regulating cell migration, adhesion, spreading, reorganization of the actin cytoskeleton, formation and disassembly of focal adhesions and cell protrusions, cell cycle progression, cell proliferation and apoptosis. Required for early embryonic development and placenta development. Required for embryonic angiogenesis, normal cardiomyocyte migration and proliferation, and normal heart development.
Synonyms FADK; FAK1; FRNK; p125FAK; pp125FAK; PPP1R71; Ptk2;
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.