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STUB1 Antibody, mAb, Rabbit

E3 ubiquitin-protein ligase which targets misfolded chaperone substrates towards proteasomal degradation.Plays a role in the maintenance of mitochondrial morphology and promotes mitophagic removal of dysfunctional mitochondria; thereby acts as a protector against apoptosis in response to cellular stress.
￥1200 在线订购包邮(港澳台除外)
A04650-50

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产品概述
Specificity This product is specific to STUB1
Host Species Rabbit
Immunogen A synthesized peptide derived from human STUB1
Species Reactivity Human; Mouse; Rat
Conjugate Unconjugated
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应用指导
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Application Recommended Usage
Western Blot 1:1000-1:2000
Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50-1:200
Immunoprecipitation (IP) 1:20-1:50
Flow Cytometry 1:20-1:100
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产品属性
Form Liquid
Storage Buffer Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Instructions Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.
Purification Affinity-chromatography
Isotype Rabbit IgG
Clonality Monoclonal
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图例
STUB1 Antibody, MAb, Rabbit

Western blot analysis of STUB1 expression in (1) HEK293 cell lysate; (2) Mouse brain lysate. »

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技术背景
Target Background E3 ubiquitin-protein ligase which targets misfolded chaperone substrates towards proteasomal degradation.Plays a role in the maintenance of mitochondrial morphology and promotes mitophagic removal of dysfunctional mitochondria; thereby acts as a protector against apoptosis in response to cellular stress.
Synonyms STUB1; CHIP; HSPABP2; NY-CO-7; SDCCAG7; UBOX1;
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.