Specificity | This product is specific to ICAM 1 |
Host Species | Rabbit |
Immunogen | A synthesized peptide derived from mouse ICAM 2 |
Species Reactivity | Mouse |
Conjugate | Unconjugated |
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product. | |||||||
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Form | Liquid |
Storage Buffer | Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
Storage Instructions | Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed. |
Purification | Affinity-chromatography |
Isotype | Rabbit IgG |
Clonality | Monoclonal |
Target Background | ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. |
Synonyms | BB2; CD54; Cell surface glycoprotein P3.58; Human rhinovirus receptor; ICAM1; intercellular adhesion molecule 1 (CD54); Intercellular adhesion molecule 1; Major group rhinovirus receptor; MALA2; MyD10; P3.58; Surface antigen of activated B cells; |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.