目录产品 » CK I alpha Antibody, mAb, Rabbit
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CK I alpha Antibody, mAb, Rabbit

Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May play a role in segregating chromosomes during mitosis.
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A04518-50

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产品概述
Specificity This product is specific to CK I alpha
Host Species Rabbit
Immunogen A synthesized peptide derived from human CK I alpha
Species Reactivity Human; Mouse; Rat
Conjugate Unconjugated
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应用指导
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Application Recommended Usage
Western Blot 1:1000-1:2000
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产品属性
Form Liquid
Storage Buffer Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Instructions Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.
Purification Affinity-chromatography
Isotype Rabbit IgG
Clonality Monoclonal
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图例
CK I Alpha Antibody, MAb, Rabbit

Western blot analysis of CSNK1A1 expression in (1) MCF7 cell lysate; (2) NIH/3T3 cell lysate. »

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技术背景
Target Background Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May play a role in segregating chromosomes during mitosis.
Synonyms CK1; CK1A; CKI alpha; CKIa; Csnk1a1; HLCDGP1;
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.