RNase L Antibody, mAb, Rabbit

Endoribonuclease that functions in the interferon (IFN) antiviral response. In INF treated and virus infected cells, RNASEL probably mediates its antiviral effects through a combination of direct cleavage of single-stranded viral RNAs, inhibition of protein synthesis through the degradation of rRNA, induction of apoptosis, and induction of other antiviral genes.

价格	￥1200 在线订购包邮(港澳台除外)
产品编号	A04467-50
规格	50 μl 100 μl 大单询价
数量
参考货期


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产品概述应用指导产品属性图例技术背景

产品概述

Specificity	This product is specific to RNase L
Host Species	Rabbit
Immunogen	A synthesized peptide derived from human RNase L
Species Reactivity	Human
Conjugate	Unconjugated

应用指导

Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.

Application	Recommended Usage
Western Blot	1:1000-1:2000

产品属性

Form	Liquid
Storage Buffer	Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Instructions	Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.
Purification	Affinity-chromatography
Isotype	Rabbit IgG
Clonality	Monoclonal

图例

Western blot analysis of RNase L expression in THP1 cell lysate. »

技术背景

Target Background	Endoribonuclease that functions in the interferon (IFN) antiviral response. In INF treated and virus infected cells, RNASEL probably mediates its antiviral effects through a combination of direct cleavage of single-stranded viral RNAs, inhibition of protein synthesis through the degradation of rRNA, induction of apoptosis, and induction of other antiviral genes.
Synonyms	PRCA1; Ribonuclease4; RibonucleaseL; RNase L; Rnasel; RNS4;

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.