目录产品 » RUVBL2 Antibody, mAb, Rabbit
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RUVBL2 Antibody, mAb, Rabbit

Possesses single-stranded DNA-stimulated ATPase and ATP-dependent DNA helicase (5' to 3') activity; hexamerization is thought to be critical for ATP hydrolysis and adjacent subunits in the ring-like structure contribute to the ATPase activity.Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A.
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A03756-50

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产品概述
Specificity This product is specific to RUVBL2
Host Species Rabbit
Immunogen A synthesized peptide derived from human RUVBL2
Species Reactivity Human; Mouse
Conjugate Unconjugated
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应用指导
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Application Recommended Usage
Western Blot 1:1000-1:2000
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产品属性
Form Liquid
Storage Buffer Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Instructions Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.
Purification Affinity-chromatography
Isotype Rabbit IgG
Clonality Monoclonal
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图例
RUVBL2 Antibody, MAb, Rabbit

Western blot analysis of Reptin / RUVBL2 expression in (1) HeLa cell lysate; (2) NIH/3T3 cell lysate. »

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技术背景
Target Background Possesses single-stranded DNA-stimulated ATPase and ATP-dependent DNA helicase (5' to 3') activity; hexamerization is thought to be critical for ATP hydrolysis and adjacent subunits in the ring-like structure contribute to the ATPase activity.Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A.
Synonyms ECP51; Reptin 52; REPTIN; RUVB2; RUVBL2; RVB2; TAP54-beta; TIH2; TIP48; TIP49b; zreptin;
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.