| Specificity |
This product is specific to mGluR2 |
| Host Species |
Rabbit |
| Immunogen |
A synthesized peptide derived from human mGluR2 |
| Species Reactivity |
Human; Mouse; Rat |
| Conjugate |
Unconjugated |
|
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product. |
| Application |
Recommended Usage |
| Western Blot |
1:1000-1:5000 |
| Immunohistochemistry (IHC) |
1:100-1:200 |
| Immunocytochemistry/Immunofluorescence (ICC/IF) |
1:50-1:200 |
| Immunohistochemistry Frozen (IHF) |
1:50-1:200 |
|
| Form |
Liquid |
| Storage Buffer |
Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| Storage Instructions |
Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed. |
| Purification |
Affinity-chromatography |
| Isotype |
Rabbit IgG |
| Clonality |
Monoclonal |
| Target Background |
G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization. |
| Synonyms |
GRM2; Glutamate receptor homolog; GPRC1B; MGlu2; Metabotropic; GLUR2; MGLUR2; |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.
