| ￥1200 在线订购包邮(港澳台除外) | |
| A03341-50 | |
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| Specificity | This product is specific to p-B Raf (T401) |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide derived from human B Raf around the phosphorylation site of T401 |
| Species Reactivity | Human; Mouse; Rat |
| Conjugate | Unconjugated |
| Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product. | |||||||||
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| Form | Liquid |
| Storage Buffer | Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| Storage Instructions | Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed. |
| Purification | Affinity-chromatography |
| Isotype | Rabbit IgG |
| Clonality | Monoclonal |
Western blot analysis of Phospho-B Raf (T401) expression in (1) PC-12 cell lysate; (2) PC-12 cell lysate treated with TPA. »
| Target Background | Protein kinase involved in the transduction of mitogenic signals from the cell membrane to the nucleus (Probable). Phosphorylates MAP2K1, and thereby activates the MAP kinase signal transduction pathway. |
| Synonyms | B-RAF; B-RAF proto-oncogene serine/threonine-protein kinase; BRAF1; RAFB1; RMIL; RMIL serine/threonine-protein kinase; c-RMIL; kinase B-Raf; |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.
