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JAM A Antibody, mAb, Rabbit

Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3.The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly.Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier.
￥1200 在线订购包邮(港澳台除外)
A03018-50

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产品概述
Specificity This product is specific to JAM A
Host Species Rabbit
Immunogen A synthesized peptide derived from human JAM A
Species Reactivity Human; Mouse; Rat
Conjugate Unconjugated
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应用指导
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Application Recommended Usage
Western Blot 1:1000-1:2000
Immunohistochemistry (IHC) 1:100-1:200
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产品属性
Form Liquid
Storage Buffer Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Instructions Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.
Purification Affinity-chromatography
Isotype Rabbit IgG
Clonality Monoclonal
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图例
JAM A Antibody, MAb, Rabbit

Western blot analysis of JAM1 expression in HeLa cell lysate. »

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技术背景
Target Background Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3.The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly.Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier.
Synonyms F11R;CD321;JAM;JAM-1;JAM-A;JAM1;JAMA;JCAM;KAT;PAM-1;Junction adhesion molecule 1;
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.