| ￥1200 在线订购包邮(港澳台除外) | |
| A02821-50 | |
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| Specificity | This product is specific to p-AS160 (T642) |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide derived from human AS160 around the phosphorylation site of T642 |
| Species Reactivity | Human |
| Conjugate | Unconjugated |
| Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product. | |||||
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| Form | Liquid |
| Storage Buffer | Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| Storage Instructions | Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed. |
| Purification | Affinity-chromatography |
| Isotype | Rabbit IgG |
| Clonality | Monoclonal |
Western blot analysis of Phospho-AS160 (T642) expression in 293T treated with insulin cell lysate. »
| Target Background | May act as a GTPase-activating protein for RAB2A, RAB8A, RAB10 and RAB14. Isoform 2 promotes insulin-induced glucose transporter SLC2A4/GLUT4 translocation at the plasma membrane, thus increasing glucose uptake. |
| Synonyms | AS160; BUB2; CDC16; NIDDM5; Tbc1d4; |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.
