| ￥1200 | |
| A02812 | |
|
|
|
|
|
|
|
|
|
| Specificity | This product is specific to Caspase 1 |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide derived from human Caspase 1 |
| Species Reactivity | Human; Rat |
| Conjugate | Unconjugated |
| Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product. | |||||||
|
|||||||
| Form | Liquid |
| Storage Buffer | Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| Storage Instructions | Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed. |
| Purification | Affinity-chromatography |
| Isotype | Rabbit IgG |
| Clonality | Monoclonal |
| Target Background | Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis. |
| Synonyms | CASP-1; ICE; IL-1 beta converting enzyme; IL-1BC; IL1BCE; caspase-1; |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.
