| ￥1200 | |
| A02542-50 | |
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| Specificity | This product is specific to Nrf 2 |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide derived from human Nrf 2 |
| Species Reactivity | Human; Mouse |
| Conjugate | Unconjugated |
| Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product. | |||||||||||||||
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| Form | Liquid |
| Storage Buffer | Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| Storage Instructions | Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed. |
| Purification | Affinity-chromatography |
| Isotype | Rabbit IgG |
| Clonality | Monoclonal |
Western blot analysis of Nrf2 expression in 293T cell treated with arsenite. »
| Target Background | Transcription factor that plays a key role in the response to oxidative stress: binds to antioxidant response (ARE) elements present in the promoter region of many cytoprotective genes, such as phase 2 detoxifying enzymes, and promotes their expression, thereby neutralizing reactive electrophiles. |
| Synonyms | Nuclear factor erythroid 2-related factor 2; Nuclear factor, erythroid derived 2, like 2; NFE2-related factor 2; NRF2; NF-E2-related factor 2; NFE2L2; NF2L2; HEBP1 |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.
