| ￥3360 | |
| A02347 | |
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| Specificity | The product is specific for humanized VHH antibodies, while also recognizing some VHH antibodies derived from camelids (including llama, alpaca, and camel). It has no cross-reactivity with mouse, rat, rabbit, goat or human immunoglobulins. |
| Host Species | Rabbit |
| Immunogen | VHH antibody |
| Conjugate | Biotin |
| Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product. | |||||||||||
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| Form | Liquid |
| Storage Buffer | Supplied in PBS (pH 7.2), containing 10 mg/ml BSA, 0.03% ProClin300 and 50% glycerol. |
| Concentration | 0.5 mg/ml |
| Storage Instructions | Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed. |
| Purification |
His-tag affinity purification.
Note: The product contains a His tag for purification purposes. |
| Isotype | Rabbit Fab |
| Clonality | Monoclonal |
| Note | GenScript can customize this product per customer's request including product size, buffer components, etc. |
| Target Background | A camelid single-domain antibody (sdAb, called Nanobody by Ablynx) is a peptide chain about 110 amino acids long comprising one variable domain of a heavy-chain antibody (VHH fragment). Like a whole antibody, a single-domain antibody is able to bind selectively to a specific antigen. Such antibodies allow a broad range of applications in biotechnical as well as therapeutic fields due to their small size, simple production, and high affinity. However, their sequences may increase the risk of immunogenicity and cause anti-drug antibody (ADA) development in humans, and thus, sdAbs are routinely humanized during development. |
| Synonyms | VHH, Nanobody, Single-Domain Antibody, sdAb, HCAb-Derived Variable Domain, Heavy chain antibody, HcAb, Heavy Chain-Only Antibody Fragment, Camelid Single-Domain Antibody, Variable Domain of Heavy Chain Antibody, Camelid antibody, Humanized sdAb, Humanized VHH |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.
