目录产品 » MonoFab Anti-Camelid VHH Antibody [Biotin], Fab
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MonoFab Anti-Camelid VHH Antibody [Biotin], Fab

The product is specific for VHH antibodies derived from camelids (including llama, alpaca, and camel), while also recognizing some humanized VHH antibodies. It has no cross-reactivity with mouse, rat, rabbit, goat or human immunoglobulins.
￥3360 在线订购包邮(港澳台除外)
A02346-200

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产品概述
Specificity The product is specific for VHH antibodies derived from camelids (including llama, alpaca, and camel), while also recognizing some humanized VHH antibodies. It has no cross-reactivity with mouse, rat, rabbit, goat or human immunoglobulins.
Host Species Rabbit
Immunogen VHH antibody
Conjugate Biotin
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应用指导
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Application Recommended Usage
ELISA 1:10-1:100
Western Blot User-optimized
Immunohistochemistry (IHC) User-optimized
Immunocytochemistry/Immunofluorescence (ICC/IF) User-optimized
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产品属性
Form Liquid
Storage Buffer Supplied in PBS (pH 7.2), containing 10 mg/ml BSA, 0.03% ProClin300 and 50% glycerol.
Concentration 0.5 mg/ml
Storage Instructions Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.
Purification His-tag affinity purification.
Note: The product contains a His tag for purification purposes.
Isotype Rabbit Fab
Clonality Monoclonal
Note GenScript can customize this product per customer's request including product size, buffer components, etc.
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图例
MonoFab Anti-Camelid VHH Antibody [Biotin], Fab

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技术背景
Target Background A camelid single-domain antibody (sdAb, called Nanobody by Ablynx) is a peptide chain about 110 amino acids long comprising one variable domain of a heavy-chain antibody (VHH fragment). Like a whole antibody, a single-domain antibody is able to bind selectively to a specific antigen. Such antibodies allow a broad range of applications in biotechnical as well as therapeutic fields due to their small size, simple production, and high affinity. However, their sequences may increase the risk of immunogenicity and cause anti-drug antibody (ADA) development in humans, and thus, sdAbs are routinely humanized during development.
Synonyms VHH, Nanobody, Single-Domain Antibody, sdAb, HCAb-Derived Variable Domain, Heavy chain antibody, HcAb, Heavy Chain-Only Antibody Fragment, Camelid Single-Domain Antibody, Variable Domain of Heavy Chain Antibody, Camelid antibody, Humanized sdAb, Humanized VHH
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.