| Specificity | The product is specific for human CD3. |
| Host Species | Mouse |
| Immunogen | Recombinant human CD3 |
| Species Reactivity | Human |
| Conjugate | Unconjugated |
| Working concentrations for specific applications should be determined by the investigators. The suitability of this antibody for applications other than those listed below has not been determined. For flow cytometric staining, the following concentration range is recommended starting points for this product and is suggested that the reagent be titrated for optimal performance for each application. | |||||
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| Form | Liquid |
| Storage Buffer | Supplied in 10 mM Sodium Citrate, 150 mM NaCl, 0.02 mg/ml Polysorbate 80, pH 5.0. |
| Concentration | 1 mg/ml |
| Endotoxin Level | < 0.5 EU/μg by gel clotting method |
| Storage Instructions | The product remains stable for 12 months at 4℃ from the date of receipt. For longer time storage, store at -80℃. Avoid repeated freeze-thaw cycles. |
| Purification | Protein A affinity column |
| Isotype | Mouse IgG2a |
| Clonality | Monoclonal |
| Note | GenScript can customize this product per customer's request including conjugations, product size, buffer components, etc. |
| Target Background | CD3 is a member of the immunoglobulin superfamily, expressed on T cells. It is composed of four distinct chains (ε, γ, δ, ζ). CD3 antigen can form a complex with the T cell receptor (TCR) to generate an activation signal in T cells, which plays an important role in TCR signal transduction and both cytotoxic T cell ( CD8 + naïve T cells) and T helper cells (CD4+ naïve T cells) activation. |
| Synonyms | CD3; cluster of differentiation 3 |
For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.