| ￥1980 在线订购包邮(港澳台除外) | |
| A01846-40 | |
|
|
|
|
|
|
|
|
|
| 咨询产品问题 | |
| Specificity | The product is specific for Pembrolizumab. This antibody serves as an excellent positive control for Pembrolizumab immunogenicity (ADA) assays. |
| Host Species | Rabbit |
| Immunogen | Pembrolizumab |
| Conjugate | Unconjugated |
| Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product. | |||||
|
|||||
| Form | Lyophilized |
| Storage Buffer | lyophilized with PBS, pH 7.4, containing 0.02% sodium azide. |
| Reconstitution | Reconstitute the lyophilized powder with deionized water (or equivalent) to an final concentration of 0.5 mg/mL. |
| Storage Instructions | The lyophilized product remains stable for 1 year at -20°C from the date of receipt. Upon reconstitution, it can be stored for 2-3 weeks at 2-8°C or for 12 months at -20°C or below. Avoid repeated freeze and thaw cycles. |
| Purification | Antigen affinity purification |
| Isotype | Rabbit IgG |
| Clonality | Polyclonal |
| Clone ID | Not applicable |
| Note | GenScript can customize this product per customer's request including product size, buffer components, etc. |
»
ELISA binding of Anti-Pembrolizumab Antibody, pAb, Rabbit (GenScript, A01846-40) with Pembrolizumab.
Coating antigen: Pembrolizumab, 1 µg/ml.
Anti-Pembrolizumab Antibody, pAb, Rabbit (GenScript, A01846-40) dilutions start from 1,000 ng/ml.
EC₅₀= 21.57 ng/ml.
»
| Target Background | Pembrolizumab (Keytruda) is a humanized monoclonal antibody that is approved by the U.S. Food and Drug Administration for the treatment of patients with unresectable or metastatic melanoma. Pembrolizumab binds to the human cell surface receptor PD-1 (Programmed Cell Death Protein 1) and blocks its interaction with PD-L1, resulting in the activation of T-cell-mediated immune responses against tumor cells.GenScript Anti-Pembrolizumab Antibody, pAb, Rabbit is produced from sera of a rabbit immunized with Pembrolizumab.. |
| Synonyms | Rabbit polyclonal to Keytruda |
| 有限使用许可与使用限制 |
This Product is provided under a limited, non-exclusive, non-transferable, and non-sublicensable end-user license strictly limited to the permitted uses set forth in GenScript’s official documentation, quotations, or written agreements. Any use beyond such scope requires GenScript’s prior written authorization or license. Except as expressly authorized in writing by GenScript, Customer shall not, and shall not permit, procure, enable, or assist any third party to: (a) commercialize or otherwise exploit the Product, including by reselling, distributing, transferring, sublicensing, or otherwise making the Product (including any product incorporating the Product) available to any third party; (b) copy, reproduce, clone, reverse clone, sequence, analyze, characterize, deconstruct, reconstruct, reverse engineer, or otherwise attempt to discover the composition, sequence, structure, binding characteristics, epitope recognition characteristics, or other proprietary features of the Product; (c) modify, derivatize, humanize, optimize, mutate, design around, or generate any variants, derivatives, fragments, substitutes, or functional equivalents of the Product; or (d) use the Product, any information derived therefrom, or any computational, AI-enabled, or sequence-based design method to develop, manufacture, offer for sale, sell, or commercialize any product or service competitive with the Product or GenScript’s products or services. All intellectual property rights and all rights not expressly granted herein are reserved by GenScript. No rights are granted by implication, estoppel, or otherwise. |
For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.
