| ￥1200 | |
| A01795-100 | |
|
|
|
|
|
|
|
|
|
| Specificity |
GenScript’s THE™ PEG Antibody, mAb, Mouse has high affinity for the PEG
backbone. The antibody binds to the variety of PEG such as PEG40K, PEG20K,
PEG5K, PEG12, PEGylated drugs and PEG conjugates. |
| Host Species | Mouse |
| Immunogen | PEG conjugated to KLH |
| Conjugate | Unconjugated |
| Working concentrations for specific applications should be empirically determined by the investigator. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the detection methods, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. | |||||||||||
|
|||||||||||
| Form | Lyophilized |
| Storage Buffer |
Lyophilized with PBS, pH 7.4, containing 0.02% sodium azide. |
| Reconstitution |
Reconstitute the lyophilized powder with deionized water (or equivalent)
to a final concentration of 0.5 mg/mL. For long-term storage, adding glycerol
to a final concentration of 50% (v/v) in the reconstituted antibody solution is
recommended. |
| Storage Instructions |
The lyophilized product remains stable for up to 1 year at -20°C from the
date of receipt. The reconstituted antibody can be stored for 2-3 weeks at
2-8°C or for up to 12 months at -20°C or below. Avoid repeated freezing and
thawing cycles. |
| Purification | Affinity chromatography |
| Isotype | Mouse IgM |
| Clonality | Monoclonal |
| Clone ID | 5E10E9 |
| Note |
Some
reagents such as Tween-20, Triton X-100 and NP-40 interfere with the PEG
antibody interactions due to their structural similarity to PEG. Antibody
solution should not contain such reagents in the assay of PEGylated molecules. GenScript can customize this product per customer's request including product size, buffer components, etc. |
| Target Background |
PEG (Polyethylene glycol) is a polyether compound with many applications
from industrial manufacturing to medicine. PEGylation is a technology that
covalently couples non-toxic, hydrophilic polyethylene glycol (PEG) to the
drug. It is an FDA-approved method for the delivery of protein drugs. PEG
modification can reduce the drug immunogenicity and antigenicity. PEGylated
drug decelerates renal excretion, improves stability towards proteolysis and
increases its half-life in blood. Accurate and sensitive quantification of PEG
conjugates is important for PEG conjugated product development and
pharmaceutical study. Polyethylene glycol (PEG) antibody is a useful tool for
the detection of PEGylated molecules. |
| Synonyms |
Anti-Polyethylene glycol antibody, mAb, Mouse |
For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.
