GenScript - Make Research Easy - The leader in molecular cloning and gene synthesis, peptide synthesis,protein and antibody engineering.

Reconstitution defines the roles of p62, NBR1 and TAX1BP1 in ubiquitin condensate formation and autophagy initiation

Authors: Eleonora Turco, Adriana Savova, Flora Gere, Luca Ferrari, Julia Romanov, Martina Schuschnig, Sascha Martens

Journal: Nat Commun

PubMed ID: 34471133

Doi: 10.1038/s41467-021-25572-w

Products & Services: Insect Expression

The structure and flexibility analysis of the synaptotagmin 1 reveal the basis of its regulation at membrane contact sites

Authors: Juan L Benavente, Dritan Siliqi, Lourdes Infantes, Laura Lagartera, Alberto Mills, Federico Gago, Noemí Ruiz-López, Miguel A Botella, María J Sánchez-Barrena, Armando Albert

Journal: Life Sci Alliance

PubMed ID: 34408000

Doi: 10.26508/lsa.202101152

Products & Services: Proteins, Expression, Isolation and Analysis

Simple and Fast DNA Based Sensor System for Screening of Small-Molecule Compounds Targeting Eukaryotic Topoisomerase 1

Authors: Kamilla Vandsø Petersen, Asier Selas, Kirstine Mejlstrup Hymøller, Karol Mizielinski, Maria Thorsager, Magnus Stougaard, Concepcion Alonso, Francisco Palacios, Yolanda Pérez-Pertejo, Rosa M Reguera, Rafael Balaña-Fouce, Birgitta R Knudsen, Cinzia Tesauro

Journal: Pharmaceutics

PubMed ID: 34452216

Doi: 10.3390/pharmaceutics13081255

Products & Services: Plasmid DNA Preparation

Light-Induced Dynamic Change of Phytochrome B and Cryptochrome 1 Stabilizes SINATs in

Authors: Jin Hu, Yinmeng Hu, Mengran Yang, Xiaotong Hu, Xuelu Wang

Journal: Front Plant Sci

PubMed ID: 34490020

Doi: 10.3389/fpls.2021.722733

Products & Services: Proteins, Expression, Isolation and Analysis

Structure of the human C9orf72-SMCR8 complex reveals a multivalent protein interaction architecture

Authors: Julia Nörpel, Simone Cavadini, Andreas D Schenk, Alexandra Graff-Meyer, Daniel Hess, Jan Seebacher, Jeffrey A Chao, Varun Bhaskar

Journal: PLoS Biol

PubMed ID: 34297726

Doi: 10.1371/journal.pbio.3001344

Products & Services: Codon Optimization

Novel insights into the immune regulatory effects of Megalobrama amblycephala intelectin on the phagocytosis and killing activity of macrophages

Authors: Yancui Zheng, Yunlong Liu, Hongping Li, Xu Wang, Minying Zhang, Xin Shen, Hanliang Cheng, Jianhe Xu, Xingqiang Wang, Hong Liu, Zhujin Ding, Xiaoheng Zhao

Journal: Mol Immunol

PubMed ID: 34247100

Doi: 10.1016/j.molimm.2021.06.008

Products & Services: Endotoxin Detection & Removal System

The disordered PCI-binding human proteins CSNAP and DSS1 have diverged in structure and function

Authors: Sarah F Ruidiaz, Jesper E Dreier, Rasmus Hartmann-Petersen, Birthe B Kragelund

Journal: Protein Sci

PubMed ID: 34272906

Doi: 10.1002/pro.4159

Products & Services: Mammalian Expression

Acid ceramidase improves mitochondrial function and oxidative stress in Niemann-Pick type C disease by repressing STARD1 expression and mitochondrial cholesterol accumulation

Authors: Sandra Torres, Estel Solsona-Vilarrasa, Susana Nuñez, Nuria Matías, Naroa Insausti-Urkia, Fernanda Castro, Mireia Casasempere, Gemma Fabriás, Josefina Casas, Carlos Enrich, José C Fernández-Checa, Carmen Garcia-Ruiz

Journal: Redox Biol

PubMed ID: 34175669

Doi: 10.1016/j.redox.2021.102052

Products & Services: Plasmid DNA Preparation

ERp44/CG9911 promotes fat storage in adipocytes by regulating ER Ca homeostasis

Authors: Youkun Bi, Yan Chang, Qun Liu, Yang Mao, Kui Zhai, Yuanli Zhou, Renjie Jiao, Guangju Ji

Journal: Aging (Albany NY)

PubMed ID: 34031268

Doi: 10.18632/aging.203063

Products & Services: Proteins, Expression, Isolation and Analysis

Receptor-like kinase BAM1 facilitates early movement of the Tobacco mosaic virus

Authors: Phu-Tri Tran, Vitaly Citovsky