资源 » 参考数据库 » 客户发表文献

至今，GenScript的服务及产品已被Cell, Nature, Science, PNAS等1300多家生物医药类杂志引用近万次，处于行业领先水平。NIH、哈佛、耶鲁、斯坦福、普林斯顿、杜克大学等约400家全球著名机构使用GenScript的基因合成、多肽服务、抗体服务和蛋白服务等成功地发表科研成果，再次证明GenScript 有能力帮助业内科学家Make research easy.

Human TM9SF4 Is a New Gene Down-Regulated by Hypoxia and Involved in Cell Adhesion of Leukemic Cells.

PLoS ONE. 2015;

PaolilloRosa，SpinelloIsabella，QuarantaMaria Teresa，PasquiniLuca，PelosiElvira，Lo CocoFrancesco，TestaUgo，LabbayeCathe

Products/Services Used	Details	Operation
Custom Vector Construction	… Prom-TM9SF4) Human HIF-1α full length cDNA was cloned into a pcDNA31(+) expression vector (pcDNA31/HIF-1α vector from GenScript, Piscataway, NJ, USA) All vectors were checked by automated sequencing In luciferase …	Get A Quote

摘要

The transmembrane 9 superfamily protein member 4， TM9SF4， belongs to the TM9SF family of proteins highly conserved through evolution. TM9SF4 homologs， previously identified in many different species， were mainly involved in cellular adhesion， innate immunity and phagocytosis. In human， the function and biological significance of TM9SF4 are currently under investigation. However， TM9SF4 was found overexpressed in human metastatic melanoma and in a small subset of acute myeloid leukemia (AMLs) and myelodysplastic syndromes， consistent with an oncogenic function of this gene.