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Cooperation of N- and C-terminal substrate transmembrane domain segments in intramembrane proteolysis by γ-secretase
Authors: Nadine T Werner, Philipp Högel, Gökhan Güner, Walter Stelzer, Manfred Wozny, Marlene Aßfalg, Stefan F Lichtenthaler, Harald Steiner, Dieter Langosch
Journal: Commun Biol
PubMed ID: 36792683
Doi: 10.1038/s42003-023-04470-5
Products & Services: Gene Synthesis   
CYCLIN-DEPENDENT KINASE 8 positively regulates oil synthesis by activating WRINKLED1 transcription
Authors: Zhiyang Zhai, Jantana K Blanford, Yingqi Cai, Jing Sun, Hui Liu, Hai Shi, Jorg Schwender, John Shanklin
Journal: New Phytol
PubMed ID: 36683527
Doi: 10.1111/nph.18764
Products & Services: Monoclonal Antibody Services   
ACE2 binding and antibody evasion in enhanced transmissibility of XBB15
Authors: Can Yue, Weiliang Song, Lei Wang, Fanchong Jian, Xiaosu Chen, Fei Gao, Zhongyang Shen, Youchun Wang, Xiangxi Wang, Yunlong Cao
Journal: Lancet Infect Dis
PubMed ID: 36746173
Doi: 10.1016/S1473-3099(23)00010-5
MTORC2 is a physiological hydrophobic motif kinase of S6 Kinase 1
Authors: Sheikh Tahir Majeed, Rabiya Majeed, Aijaz A Malik, Khurshid Iqbal Andrabi
Journal: Biochim Biophys Acta Mol Cell Res
PubMed ID: 36858209
Doi: 10.1016/j.bbamcr.2023.119449
Products & Services: Catalog Peptides   
A Physiologically Responsive Nanocomposite Hydrogel for Treatment of Head and Neck Squamous Cell Carcinoma via Proteolysis-Targeting Chimeras Enhanced Immunotherapy
Authors: Yaping Wu, Xiaowei Chang, Guizhu Yang, Li Chen, Qi Wu, Jiamin Gao, Ran Tian, Wenyun Mu, John Justin Gooding, Xin Chen, Shuyang Sun
Journal: Adv Mater
PubMed ID: 36656993
Doi: 10.1002/adma.202210787
Products & Services: Peptide Synthesis   
Functionalized biomimetic nanoparticles combining programmed death-1/programmed death-ligand 1 blockade with photothermal ablation for enhanced colorectal cancer immunotherapy.
Authors: Yuchen Xiao, Tianchuan Zhu, Qi Zeng, Qingqin Tan, Guanmin Jiang, Xi Huang
Journal: Acta Biomater
PubMed ID: 36442821
Doi: 10.1016/j.actbio.2022.11.043
SARS-CoV-2 Main Protease Targets Host Selenoproteins and Glutathione Biosynthesis for Knockdown via Proteolysis, Potentially Disrupting the Thioredoxin and Glutaredoxin Redox Cycles
Authors: Ignacio A Gallardo, Daniel A Todd, Stella T Lima, Jonathan R Chekan, Norman H Chiu, Ethan Will Taylor
Journal: Antioxidants (Basel)
PubMed ID: 36978807
Doi: 10.3390/antiox12030559
Phosphorylation of TRF2 promotes its interaction with TIN2 and regulates DNA damage response at telomeres
Authors: Radka Storchova, Matous Palek, Natalie Palkova, Pavel Veverka, Tomas Brom, Ctirad Hofr, Libor Macurek
Journal: Nucleic Acids Res
PubMed ID: 36651296
Doi: 10.1093/nar/gkac1269
Products & Services: Peptide Synthesis   
Chikungunya Virus and Its Envelope Protein E2 Induce Hyperalgesia in Mice: Inhibition by Anti-E2 Monoclonal Antibodies and by Targeting TRPV1
Authors: Carina Z Segato-Vendrameto, Camila Zanluca, Amanda Z Zucoloto, Tiago H Zaninelli, Mariana M Bertozzi, Telma Saraiva-Santos, Camila R Ferraz, Larissa Staurengo-Ferrari, Stephanie Badaro-Garcia, Marília F Manchope, Amanda M Dionisio, Felipe A Pinho-Ribeiro, Sergio M Borghi, Ana Luiza Pamplona Mosimann, Rubia Casagrande, Juliano Bordignon, Victor Fattori, Claudia N Duarte Dos Santos, Waldiceu A Verri
Journal: Cells
PubMed ID: 36831223
Doi: 10.3390/cells12040556
Products & Services: Codon Optimization   
How Many Sirtuin Genes Are Out There? Evolution of Sirtuin Genes in Vertebrates With a Description of a New Family Member
Authors: Juan C Opazo, Michael W Vandewege, Federico G Hoffmann, Kattina Zavala, Catalina Meléndez, Charlotte Luchsinger, Viviana A Cavieres, Luis Vargas-Chacoff, Francisco J Morera, Patricia V Burgos, Cheril Tapia-Rojas, Gonzalo A Mardones
Journal: Mol Biol Evol
PubMed ID: 36656997
Doi: 10.1093/molbev/msad014
Products & Services: Plasmid DNA Preparation   

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