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Co-delivery of Cas9 mRNA and guide RNAs edits hepatitis B virus episomal and integration DNA in mouse and tree shrew models
Authors: Junzhu Yi, Xinlin Lei, Fangteng Guo, Qiubing Chen, Xueyong Chen, Kaitao Zhao, Chengliang Zhu, Xiaoming Cheng, Jiangwei Lin, Hao Yin, Yuchen Xia
Journal: Antiviral research
PubMed ID: 37142191
Doi: 10.1016/j.antiviral.2023.105618
Products & Services: CRISPR RNAs/Cas9 Proteins(INACTIVE)   
Functionalized Metal–Organic Framework-Modified Hydrogel That Breaks the Vicious Cycle of Inflammation and ROS for Repairing of Diabetic Bone Defects
Authors: An Lao, Jiaqing Wu, Dejian Li, Aili Shen, Yaxin Li, Yu Zhuang, Kaili Lin, Jianyong Wu, Jiaqiang Liu
Journal: Small
PubMed ID: 37183293
Doi: smll.202206919
Products & Services: Proteins, Expression, Isolation and Analysis   
Immunogenic SARS-CoV-2 S and N Protein Peptide and Cytokine Combinations as Biomarkers for Early Prediction of Fatal COVID-19
Authors: Ekaterina Martynova , Shaimaa Hamza , Maria Markelova , Ekaterina Garanina , Yuriy Davidyuk , Venera Shakirova , Neha Kaushal , Manoj Baranwal , Robert J Stott-Marshall , Toshana L Foster , Albert Rizvanov , Svetlana Khaiboullina
Journal: Front Immunol .
PubMed ID: 35386707
Doi: 10.3389/fimmu.2022.830715
Products & Services: Peptide Synthesis   
In vitro reconstitution of SARS-CoV-2 Nsp1-induced mRNA cleavage reveals the key roles of the N-terminal domain of Nsp1 and the RRM domain of eIF3g
Authors: Irina S. Abaeva, Yani Arhab, Anna Miscicka, Christopher U.T. Hellen, and Tatyana V. Pestova
Journal: bioRxiv .
PubMed ID: 37292671
Doi: 10.1101/gad.350829.123
Products & Services: Gene Synthesis   
Topically Administered NOX4 Inhibitor, GLX7013114, Is Efficacious in Treating the Early Pathological Events of Diabetic Retinopathy
Authors: Stavroula Dionysopoulou, Per Wikstrom, Claudio Bucolo, Giovanni Luca Romano, Vincenzo Micale, Richard Svensson, Dimitris Spyridakos, Niki Mastrodimou, Spiros Georgakis, Panayotis Verginis, Erik Walum, Kyriaki Thermos
Journal: Diabetes
PubMed ID: 36821829
Doi: 10.2337/db22-0515
Products & Services: Proteins, Expression, Isolation and Analysis   
The Nucleocapsid Proteins of SARS-CoV-2 and Its Close Relative Bat Coronavirus RaTG13 Are Capable of Inhibiting PKR- and RNase L-Mediated Antiviral Pathways
Authors: Kyle LeBlanc, Jessie Lynch, Christine Layne, Robert Vendramelli, Angela Sloan, Nikesh Tailor, Yvon Deschambault, Fushun Zhang, Darwyn Kobasa, David Safronetz, Yan Xiang, Jingxin Cao
Journal: Microbiol Spectr
PubMed ID: 37154717
Doi: 10.1128/spectrum.00994-23
Products & Services: Proteins, Expression, Isolation and Analysis   
KRAS mutation-induced TOPK overexpression contributes to tumour progression in non-small cell lung cancer
Authors: Chang Cai, Shuo Yao, Yanmei Zou, Hui Lu, Xiuqiong Chen, Yali Wang, Kun Zheng, Feng Zhu, Yihua Wang, Hua Xiong, Junfei Zhu
Journal: J Cell Mol Med
PubMed ID: 37226642
Doi: 10.1111/jcmm.17640
Products & Services: Proteins, Expression, Isolation and Analysis   
Redundant actions of neuropeptides encoded by the dh-pban gene for larval color pattern formation in the oriental armyworm Mythimnaseparata
Authors: Yu Shirai, Hajime Ono, Takaaki Daimon
Journal: Insect Biochem Mol Biol
PubMed ID: 37146697
Doi: 10.1016/j.ibmb.2023.103955
Products & Services: Peptide Synthesis   
Detection of viral RNAs at ambient temperature via reporter proteins produced through the target-splinted ligation of DNA probes
Authors: Elizabeth A Phillips, Adam D Silverman, Aric Joneja, Michael Liu, Carl Brown, Paul Carlson, Christine Coticchia, Kristen Shytle, Alex Larsen, Nadish Goyal, Vincent Cai, Jason Huang, Jennifer E Hickey, Emily Ryan, Joycelynn Acheampong, Pradeep Ramesh, James J Collins, William J Blake
Journal: Nat Biomed Eng
PubMed ID: 37142844
Doi: 10.1038/s41551-023-01028-y
Products & Services: Proteins, Expression, Isolation and Analysis   
Modeling cell-mediated immunity in human type 1 diabetes by engineering autoreactive CD8 T cells
Authors: Leeana D Peters, Wen-I Yeh, Juan M Arnoletti, Matthew E Brown, Amanda L Posgai, Clayton E Mathews, Todd M Brusko
Journal: Front Immunol
PubMed ID: 37325626
Doi: 10.3389/fimmu.2023.1142648
Products & Services: Peptide Synthesis   

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