目录产品 » NPR1/NPRA mFc Chimera, Mouse
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NPR1/NPRA mFc Chimera, Mouse

NPR1 (natriuretic peptide receptor 1), a receptor of ANP (atrial natriuretic peptide) whitch acting through NPR1, provokes hypotension. NPR1 was abundantly expressed in endothelial cells and smooth muscle cells of small arteries and arterioles. NPR1 plays a crucial role in ANP-mediated blood pressure regulation, presumably by a mechanism that is RGS2-dependent in the acute phase and RGS2-independent in the chronic phase.
￥3800
Z06288-100

产品简介
Species Mouse
Protein Construction
NPR1/NPRA (Ser29-Glu469)_x000D_
Accession # NP_032753.5		 mFc (IgG1)
N-term C-term
Purity > 95% as determined by Bis-Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 74.92 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 75-105 kDa based on Bis-Tris PAGE result.
Formulation Supplied as 0.22 μm filtered solution in PBS (pH 7.4).
Concentration Verified by one or more methods from 0.64mg/ml A280/Bioactivity/BCA/Bradford.
Storage & Stability This product remains stable for 6 months at -80°C or below. Avoid repeated freeze-thaw cycles.
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技术背景
Target Background NPR1 (natriuretic peptide receptor 1), a receptor of ANP (atrial natriuretic peptide) whitch acting through NPR1, provokes hypotension. NPR1 was abundantly expressed in endothelial cells and smooth muscle cells of small arteries and arterioles. NPR1 plays a crucial role in ANP-mediated blood pressure regulation, presumably by a mechanism that is RGS2-dependent in the acute phase and RGS2-independent in the chronic phase.
Synonyms ANP-A; ANPR-A; NPR-A; GC-A; ANPRA
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.