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Midkine, His, Mouse

Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive gene during embryogenesis, but currently viewed as a multifaceted factor contributing to both normal tissue homeostasis and disease development. Midkine is abnormally expressed at high levels in various human malignancies and acts as a mediator for the acquisition of critical hallmarks of cancer, including cell growth, survival, metastasis, migration, and angiogenesis.
￥3300
Z06270-100

产品简介
Species Mouse
Protein Construction
His Midkine (Lys23-Asp140)_x000D_
Accession # P12025
N-term C-term
Purity > 95% as determined by Bis-Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System E.coli
Theoretical Molecular Weight 14.03 kDa
Apparent Molecular Weight The protein migrates to 18­23 kDa based on Bis­Tris PAGE result.
Formulation Supplied as 0.22μm filtered solution in PBS, 350mM NaCl, 200mM L-arginine (pH 7.4).
Concentration Verified by one or more methods from 0.64mg/ml A280/Bioactivity/BCA/Bradford.
Storage & Stability This product remains stable for 6 months at -80°C or below. Avoid repeated freeze-thaw cycles.
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技术背景
Target Background Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive gene during embryogenesis, but currently viewed as a multifaceted factor contributing to both normal tissue homeostasis and disease development. Midkine is abnormally expressed at high levels in various human malignancies and acts as a mediator for the acquisition of critical hallmarks of cancer, including cell growth, survival, metastasis, migration, and angiogenesis.
Synonyms MK; ARAP; MDK; MEK; MK1; MKARAP; NEGF2
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.