| ￥4100 | |
| Z06225-100 | |
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| Species | Mouse | ||||
| Protein Construction |
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| Purity |
> 95% as determined by BisTris PAGE > 95% as determined by HPLC |
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| Endotoxin Level | Less than 1EU per μg by the LAL method. | ||||
| Expression System | HEK293 | ||||
| Theoretical Molecular Weight | 131.48 kDa (ITGAV) and 80.80 kDa (ITGB3) | ||||
| Apparent Molecular Weight | Due to enzyme lysis and glycosylation, the protein migrates to 90-130 kDa based on Bis-Tris PAGE result. | ||||
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). | ||||
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. | ||||
| Storage & Stability | Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles. |
The purity of Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer, His, Mouse is greater than 95% as determined by SEC-HPLC. »
Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer, His, Mouse on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »
| Target Background | ITGAV&ITGB3 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGAV&ITGB3 binds to FGF1 and this binding is essential for FGF1 signaling. ITGAV&ITGB3 binds to FGF2 and this binding is essential for FGF2 signaling. ITGAV&ITGB3 binds to IGF1 and this binding is essential for IGF1 signaling. ITGAV&ITGB3 binds to IGF2 and this binding is essential for IGF2 signaling. |
| Synonyms | αVβ3; Integrin alpha V beta 3; beta3; alphaV; ITGAV&ITGB3; Integrin alpha V β 3; β3 |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.
