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DDC, His, Mouse

Aromatic L-amino acid decarboxylase (AADC) deficiency is a rare genetic disorder characterized by deficient synthesis of dopamine and serotonin. It presents in early infancy, and causes severe developmental disability and lifelong motor, behavioral, and autonomic symptoms including oculogyric crises (OGC), sleep disorder, and mood disturbance.
¥3300
Z06082-100

Species Mouse
Protein Construction
DDC (Met1-Glu480)_x000D_
Accession # O88533
His
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its ability to convert the substrate 3, 4­dihydroxy L­phenylalanine (L­Dopa) to 3, 4­dihydroxyphenylethylamine (dopamine). The dopamine product is measured by its absorbance at 340 nm after derivatization with trinitrobenzene sulfonic acid. Test result meets the standard.
Expression System Baculovirus-Insect Cells
Theoretical Molecular Weight 55.40 kDa
Apparent Molecular Weight The protein has a predicted MW of 55.40 kDa same as Bis-Tris PAGE result.
Formulation Supplied as 0.22 μm filtered solution in 20mM Tris, 0.3M NaCl, 10% Glycerol (pH 8.0).
Concentration Verified by one or more methods from 0.64mg/ml A280/Bioactivity/BCA/Bradford.
Storage & Stability This product remains stable for 6 months at -80°C or below. Avoid repeated freeze-thaw cycles.
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Target Background Aromatic L-amino acid decarboxylase (AADC) deficiency is a rare genetic disorder characterized by deficient synthesis of dopamine and serotonin. It presents in early infancy, and causes severe developmental disability and lifelong motor, behavioral, and autonomic symptoms including oculogyric crises (OGC), sleep disorder, and mood disturbance.
Synonyms AADC
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.