目录产品 » TSLP (R127A, R130A), His & Avi, Human
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TSLP (R127A, R130A), His & Avi, Human

Thymic Stromal Lymphopoietin (TSLP) was originally identified as an activity from the conditioned medium of a mouse thymic stromal cell line that promoted the development of B cells. Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c dendritic cells. Can induce allergic inflammation by directly activating mast cells.
￥3300
Z05928-100

产品简介
Species Human
Protein Construction
TSLP (R127A, R130A) [Tyr29-Gln159(R127A,R130A)]
Accession # Q969D9-1		 His Avi
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
> 95% as determined by HPLC
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Immobilized TSLP (R127A, R130A), His & Avi, Human at 2μg/ml (100μl/Well). Dose response curve for Human TSLPR, hFc Tag. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 17.7 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 25-35 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4).
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.
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技术背景
Target Background Thymic Stromal Lymphopoietin (TSLP) was originally identified as an activity from the conditioned medium of a mouse thymic stromal cell line that promoted the development of B cells. Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c dendritic cells. Can induce allergic inflammation by directly activating mast cells.
Synonyms thymic stromal lymphopoietin; TSLP
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.