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MVK, His & GST & Strep-II, Human

Mevalonate kinase (MK) is an essential enzyme in the mevalonate pathway which produces numerous cellular isoprenoids. The enzyme has been characterized both at the biochemical and the molecular level in a variety of organisms. Despite the fact that mevalonate kinase is not the rate-limiting enzyme in isoprenoid biosynthesis, its activity is subject to feedback regulation by the branch-point intermediates geranyldiphosphate, farnesyldiphosphate and geranylgeranyldiphosphate.
￥3300
Z05663-100

产品简介
Species Human
Protein Construction
GST His MVK (Met1-Leu396)_x000D_
Accession # Q03426		 Strep-II
N-term C-term
Purity > 90% as determined by Bis-Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System Baculovirus-Insect Cells
Theoretical Molecular Weight 72.23 kDa
Apparent Molecular Weight The protein migrates to 55-70 kDa based on Bis-Tris PAGE result.
Formulation Supplied as 0.22 μm filtered solution in 20mM Tris, 500mM NaCl, 2mM DTT, 10% glycerol (pH 7.4).
Concentration Verified by one or more methods from 0.64mg/ml A280/Bioactivity/BCA/Bradford.
Storage & Stability This product remains stable for 6 months at -80°C or below. Avoid repeated freeze-thaw cycles.
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技术背景
Target Background Mevalonate kinase (MK) is an essential enzyme in the mevalonate pathway which produces numerous cellular isoprenoids. The enzyme has been characterized both at the biochemical and the molecular level in a variety of organisms. Despite the fact that mevalonate kinase is not the rate-limiting enzyme in isoprenoid biosynthesis, its activity is subject to feedback regulation by the branch-point intermediates geranyldiphosphate, farnesyldiphosphate and geranylgeranyldiphosphate.
Synonyms MK; LRBP; POROK3; MVLK
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.