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ITK, GST, Human

Itk/Emt, a tec family tyrosine kinase, is important for T-cell development and activation through the antigen receptor. Itk/Emt can induce the generation of important second signals (PKC, Ca2+) and can modulate their duration by maintaining the stability of scaffolding complexes through regulation of cytoskeletal reorganization.
¥3800
Z05538-100

Species Human
Protein Construction
GST ITK (Arg352-Leu620)_x000D_
Accession # NP_005537.3
N-term C-term
Purity > 95% as determined by Bis-Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System Baculovirus-Insect Cells
Theoretical Molecular Weight 57.33 kDa
Apparent Molecular Weight The protein has a predicted MW of 57.33 kDa same as Bis-Tris PAGE result.
Formulation Supplied as 0.22 μm filtered solution in 50mM Tris, 150mM NaCl, 25% glycerol, 0.5mM PMSF, 0.5 mM TCEP, 0.1mM EDTA, 0.5mM GSH (pH 7.5).
Concentration Verified by one or more methods from 0.64mg/ml A280/Bioactivity/BCA/Bradford.
Storage & Stability This product remains stable for 6 months at -80°C or below. Avoid repeated freeze-thaw cycles.
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Target Background Itk/Emt, a tec family tyrosine kinase, is important for T-cell development and activation through the antigen receptor. Itk/Emt can induce the generation of important second signals (PKC, Ca2+) and can modulate their duration by maintaining the stability of scaffolding complexes through regulation of cytoskeletal reorganization.
Synonyms Kinase EMT; ITK; EMT; LYK; T-cell-specific kinase;
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.