目录产品 » PKA/PRKACA, His, Canine
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PKA/PRKACA, His, Canine

The cAMP-dependent protein kinase PKA is a well-characterized member of the serine-threonine protein AGC kinase family and is the effector kinase of cAMP signaling. As such, PKA is involved in the control of a wide variety of cellular processes including metabolism, cell growth, gene expression and apoptosis. cAMP-dependent PKA signaling pathways play important roles during infection and virulence of various pathogens. Since fluxes in cAMP are involved in multiple intracellular functions, a variety of different pathological infectious processes can be affected by PKA signaling pathways.
￥3000
Z04714-100

产品简介
Species Canine
Protein Construction
His PKA/PRKACA (Gly2-Phe350)_x000D_
Accession # NP_001003032.1
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE 
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System E.coli
Theoretical Molecular Weight 41.51 kDa
Apparent Molecular Weight The protein has a predicted MW of 41.51 kDa same as Bis-Tris PAGE result.
Formulation Supplied as 0.22μm filtered solution in PBS, 200mM NaCl (pH 7.4).
Concentration Verified by one or more methods from 0.64mg/ml A280/Bioactivity/BCA/Bradford.
Storage & Stability This product remains stable for 6 months at -80°C or below. Avoid repeated freeze-thaw cycles.
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技术背景
Target Background The cAMP-dependent protein kinase PKA is a well-characterized member of the serine-threonine protein AGC kinase family and is the effector kinase of cAMP signaling. As such, PKA is involved in the control of a wide variety of cellular processes including metabolism, cell growth, gene expression and apoptosis. cAMP-dependent PKA signaling pathways play important roles during infection and virulence of various pathogens. Since fluxes in cAMP are involved in multiple intracellular functions, a variety of different pathological infectious processes can be affected by PKA signaling pathways.
Synonyms PRKACA; PKA C-alpha; PKACA; PKA C alpha; PPNAD4
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.