目录产品 » Mature TGF beta 3[Biotin], Avi, Human
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Mature TGF beta 3[Biotin], Avi, Human

Transforming growth factor-beta 3 is a cytokine which is involved in cell growth regulation and differentiation, stimulation of extracellular matrix and modulation of immune responses. TGF beta 3 RNA is expressed in a diverse array of tissues including perichondrium, bone, intervertebral discs, mesenteries, pleura, heart, lung, palate, and amnion, as well as in central nervous system (CNS) structures such as the meninges, choroid plexus and the olfactory bulbs. Furthermore, in several organ systems, TGF beta 3 transcripts are expressed during periods of active morphogenesis suggesting that the protein may be an important factor for the growth and differentiation of many embryonic tissues.
￥6600
Z04554-100

产品简介
Species Human
Protein Construction
Mature TGF beta 3 (Ala301-Ser412)
Accession # P10600-1		 Avi
N-term C-term
Conjugate Biotin
Purity > 95% as determined by Bis-Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Biological Activity Measured by its binding ability in a functional ELISA. Immobilized Human TGF­beta RII, mFc Tag at 1μg/ml (100μl/well) on the plate can bind Mature TGF beta 3[Biotin], Avi, Human. Test result was comparable to standard batch.
Expression System HEK293
Theoretical Molecular Weight 14.53 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 15-20 kDa based on Bis-Tris PAGE result.
Formulation Lyophilized from 0.22μm filtered solution in 4mM HCl.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in 4mM HCl.
Storage & Stability Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles.
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图例
Mature TGF Beta 3[Biotin], Avi, Human

Immobilized Human TGF-beta RII, mFc Tag at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Mature TGF beta 3[Biotin], Avi, Human, Avi Tag with the EC50 of 25.8 ng/ml determined by ELISA. »

Mature TGF Beta 3[Biotin], Avi, Human

Mature TGF beta 3[Biotin], Avi, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »

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技术背景
Target Background Transforming growth factor-beta 3 is a cytokine which is involved in cell growth regulation and differentiation, stimulation of extracellular matrix and modulation of immune responses. TGF beta 3 RNA is expressed in a diverse array of tissues including perichondrium, bone, intervertebral discs, mesenteries, pleura, heart, lung, palate, and amnion, as well as in central nervous system (CNS) structures such as the meninges, choroid plexus and the olfactory bulbs. Furthermore, in several organ systems, TGF beta 3 transcripts are expressed during periods of active morphogenesis suggesting that the protein may be an important factor for the growth and differentiation of many embryonic tissues.
Synonyms TGF-beta-3; LAP; TGFB3; ARVD; ARVD1; RNHF;TGF-β-3
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.