目录产品 » LILRB4/CD85k/ILT3 SR&Domain 2[Biotin], His & Avi, Human
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LILRB4/CD85k/ILT3 SR&Domain 2[Biotin], His & Avi, Human

LILRB4,also known as CD85k and LIR-5, ILT3, is an approximately 60 kDa transmembrane glycoprotein that negatively regulates immune cell activation. Mature human ILT3 consists of a 238 amino acid (aa) extracellular domain with two Ig-like domains, a 21 aa transmembrane segment, and a 168 aa cytoplasmic domain with 3 immunoreceptor tyrosine-based inhibitory motifs (ITIM).LILRB4 is receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles.
￥7400
Z04547-100

产品简介
Species Human
Protein Construction
LILRB4/CD85k/ILT3 SR&Domain 2[Biotin] (Gly119-Glu259)_x000D_
Accession # AAH26309.1		 His Avi
N-term C-term
Purity > 95% as determined by Bis-Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 18.16 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 32-45 kDa based on Bis-Tris PAGE result.
Formulation Supplied as 0.22μm filtered solution in PBS (pH 7.4).
Concentration Verified by one or more methods from 0.64mg/ml A280/Bioactivity/BCA/Bradford.
Storage & Stability This product remains stable for 6 months at -80°C or below. Avoid repeated freeze-thaw cycles.
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技术背景
Target Background LILRB4,also known as CD85k and LIR-5, ILT3, is an approximately 60 kDa transmembrane glycoprotein that negatively regulates immune cell activation. Mature human ILT3 consists of a 238 amino acid (aa) extracellular domain with two Ig-like domains, a 21 aa transmembrane segment, and a 168 aa cytoplasmic domain with 3 immunoreceptor tyrosine-based inhibitory motifs (ITIM).LILRB4 is receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles.
Synonyms HM18; ILT3; ILT-3; LILRB4; LIR5; CD85K
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.