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DLL3 Domain (352-479), His&Avi, Human

Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity).
¥3300
Z03952-100

Species Human
Protein Construction
DLL3 Domain (352-479) (Lys352-Ala479)_x000D_
Accession # Q9NYJ7­1
His Avi
N-term C-term
Purity > 95% as determined by Bis­Tris PAGE
Endotoxin Level Less than 1EU per μg by the LAL method.
Expression System HEK293
Theoretical Molecular Weight 17.30 kDa
Apparent Molecular Weight Due to glycosylation, the protein migrates to 20-25 kDa based on Bis-Tris PAGE result.
Formulation Supplied as 0.22 μm filtered solution in PBS, 100mM L-Arginine (pH 7.4).
Concentration Verified by one or more methods from 0.64mg/ml A280/Bioactivity/BCA/Bradford.
Storage & Stability This product remains stable for 6 months at -80°C or below. Avoid repeated freeze-thaw cycles.
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Target Background Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity).
Synonyms Delta3; DLL3; Pudgy; SCDO1; SCDO1delta3
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For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.