Species |
Cynomolgus/Rhesus macaque |
Protein Construction |
Her3 (Ser20-His641) Accession # XP_005571238.1/G7N7B1 |
His |
N-term |
C-term |
|
Purity |
> 95% as determined by Bis-Tris PAGE
> 95% as determined by HPLC |
Endotoxin Level |
Less than 1EU per μg by the LAL method. |
Biological Activity |
Immobilized Her3, His,Cynomolgus/Rhesus macaque (Cat.No.: Z03909) at 1 μg/ml (100μl/Well) on the platecan bind Human NRG1 Beta 1, hFc Tag |
Expression System |
HEK293 |
Theoretical Molecular Weight |
69.54 kDa |
Apparent Molecular Weight |
Due to glycosylation, the protein migrates to 85-105 kDa based on Bis-Tris PAGE result. |
Formulation |
Lyophilized from a 0.22 μm filtered solution in PBS, pH 7.4. |
Reconstitution |
It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH2O more than 100 μg/ml. |
Storage & Stability |
Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles. |

Immobilized Her3, His, Cynomolgus/Rhesus macaque at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Human NRG1 Beta 1, hFc Tag with the EC50 of 0.12 μg/ml determined by ELISA.

The purity of Her3, His, Cynomolgus/Rhesus macaque is greater than 95% as determined by SEC-HPLC.

Her3, His, Cynomolgus/Rhesus macaque on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
Target Background |
Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and Schwann cells. Monomeric Her3 serves as a low affinity receptor for the heregulins (HRG). |
Synonyms |
ErbB3; ErbB-3; HER3; HER3c-erbB-3; LCCS2; MDA-BF-1; MGC88033; p180-ErbB3; p45-sErbB3; p85-sErbB3; ERBB3 |
For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.