| ￥2950 | |
| Z03909-100 | |
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| Species | Cynomolgus/Rhesus macaque | ||||
| Protein Construction |
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| Purity |
> 95% as determined by Bis-Tris PAGE > 95% as determined by HPLC |
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| Endotoxin Level | Less than 1EU per μg by the LAL method. | ||||
| Biological Activity | Immobilized Her3, His,Cynomolgus/Rhesus macaque (Cat.No.: Z03909) at 1 μg/ml (100μl/Well) on the platecan bind Human NRG1 Beta 1, hFc Tag | ||||
| Expression System | HEK293 | ||||
| Theoretical Molecular Weight | 69.54 kDa | ||||
| Apparent Molecular Weight | Due to glycosylation, the protein migrates to 85-105 kDa based on Bis-Tris PAGE result. | ||||
| Formulation | Lyophilized from a 0.22 μm filtered solution in PBS, pH 7.4. | ||||
| Reconstitution | It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH2O more than 100 μg/ml. | ||||
| Storage & Stability | Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles. |
Immobilized Her3, His, Cynomolgus/Rhesus macaque at 1 μg/ml (100 μl/well) on the plate. Dose response curve for Human NRG1 Beta 1, hFc Tag with the EC50 of 0.12 μg/ml determined by ELISA. »
The purity of Her3, His, Cynomolgus/Rhesus macaque is greater than 95% as determined by SEC-HPLC. »
Her3, His, Cynomolgus/Rhesus macaque on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. »
Immobilized Her3, His,Cynomolgus/Rhesus macaque, His Tag at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-HER3 Antibody, hFc Tag with the EC50 of 8.9 ng/ml determined by ELISA. »
| Target Background | Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and Schwann cells. Monomeric Her3 serves as a low affinity receptor for the heregulins (HRG). |
| Synonyms | ErbB3; ErbB-3; HER3; HER3c-erbB-3; LCCS2; MDA-BF-1; MGC88033; p180-ErbB3; p45-sErbB3; p85-sErbB3; ERBB3 |
For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.
