| Species |
Human |
| Protein Construction |
Her3/ErbB3 (Ser20-Thr643)
Accession # P21860-1 |
His |
Avi |
| N-term |
|
C-term |
|
| Conjugate |
FITC |
| Purity |
> 95% as determined by Bis-Tris PAGE
|
| Endotoxin Level |
Less than 1EU per μg by the LAL method. |
| Biological Activity |
Immobilized Her3/ErbB3[FITC], His & Avi, Human (Cat.No.: Z03908) at 5 μg/ml (100μl/Well) on the plate can bind Human NRG1 Beta 1, hFc Tag |
| Expression System |
HEK293 |
| Theoretical Molecular Weight |
71.6 kDa |
| Apparent Molecular Weight |
Due to glycosylation, the protein migrates to 72-75 kDa based on Bis-Tris PAGE result. |
| Formulation |
Lyophilized from a 0.22 μm filtered solution in HER-HM403F. |
| Reconstitution |
It is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH2O more than 100 μg/ml. |
| Storage & Stability |
Upon receiving, the product remains stable up to 6 months at -20 °C or below. Upon reconstitution, the product should be stable for 3 months at -80 °C. Avoid repeated freeze-thaw cycles. |
![Her3/ErbB3[FITC], His & Avi, Human](/product/documents/down?doc_name=Z03908 PAGE.png&file=scm_files/productFile_notes/2025/03/12/Z03908 PAGE.png "Her3/ErbB3[FITC], His & Avi, Human")
Her3/ErbB3[FITC], His & Avi, Human on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
![Her3/ErbB3[FITC], His & Avi, Human](/product/documents/down?doc_name=Z03908 ELISA.jpg&file=scm_files/productFile_notes/2025/03/12/Z03908 ELISA.jpg "Her3/ErbB3[FITC], His & Avi, Human")
Immobilized Her3/ErbB3[FITC], His & Avi, Human at 2 μg/ml (100 μl/well) on the plate. Dose response curve for Human NRG1 Beta 1, hFc Tag with the EC50 of 28.4 ng/ml determined by ELISA.
| Target Background |
Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors.Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and Schwann cells. Monomeric Her3 serves as a low affinity receptor for the heregulins (HRG). |
| Synonyms |
ErbB3; ErbB-3; HER3; HER3c-erbB-3; LCCS2; MDA-BF-1; MGC88033; p180-ErbB3; p45-sErbB3; p85-sErbB3; ERBB3 |
For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.
