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目录产品 » SARS-CoV-2 Spike protein (S1, E484K, His Tag)
SARS-CoV-2 Spike Protein (S1, E484K, His Tag)

Immobilized ACE-2 Fc Chimera, Human (Cat. No. Z03484) at 2 μg/mL can bind SARS-CoV-2 Spike protein (S1, E484K, His Tag) (Cat. No. Z03529) with a serial dilution.
THETM His Tag Antibody [HRP], mAb, Mouse (Cat.No.A00612) is used as a secondary antibody (0.2 μg/mL).

SARS-CoV-2 Spike Protein (S1, E484K, His Tag)

Lane 1: 1μg of SARS-CoV-2 Spike protein (S1, E484K, His Tag), reducing(R)
> 95% as analyzed by SDS-PAGE

SARS-CoV-2 Spike protein (S1, E484K, His Tag)

该产品即将停产。
SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as 2019-nCoV (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold to severe diseases. SARS-CoV-2 Spike Protein is composed of S1 domain and S2 domain. The E484K Spike mutation is of significant concern as it has been identified not only in three of the global variants, but also in the newly described American variants. It has been observed in vitro that this mutation alters the shape of the proteins in the viral spike which can potentially mask the antigenic portion from antibodies. There has been much speculation as whether this mutation may impact the effectiveness of monoclonal antibody treatments and cause reinfection in some patients.
Z03529
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Species SARS-CoV-2
Protein Construction
S1 protein [Gln14-Arg685 (E484K)]
Accession # P0DTC2
Poly-His
N-term C-term
Purity > 90% as analyzed by SDS-PAGE
Endotoxin Level < 0.2 EU/μg of protein by gel clotting method
Biological Activity SARS-CoV-2 Spike protein (S1, E484K, His Tag) can bind with human ACE2 (Cat. No.: Z03484) in functional ELISA assay.
Expression System 293 Cells
Theoretical Molecular Weight 79 kDa
Formulation Supplied as a solution in PBS pH 7.4
Concentration Please refer to the COA for the specific lot.
Storage & Stability Upon receiving, this product remains stable for up to 6 months at -20°C or below. Avoid repeated freeze-thaw cycles.

  • SARS-CoV-2 Spike Protein (S1, E484K, His Tag)
  • SARS-CoV-2 Spike Protein (S1, E484K, His Tag)

    Immobilized ACE-2 Fc Chimera, Human (Cat. No. Z03484) at 2 μg/mL can bind SARS-CoV-2 Spike protein (S1, E484K, His Tag) (Cat. No. Z03529) with a serial dilution.
    THETM His Tag Antibody [HRP], mAb, Mouse (Cat.No.A00612) is used as a secondary antibody (0.2 μg/mL).

  • SARS-CoV-2 Spike Protein (S1, E484K, His Tag)
  • SARS-CoV-2 Spike Protein (S1, E484K, His Tag)

    Lane 1: 1μg of SARS-CoV-2 Spike protein (S1, E484K, His Tag), reducing(R)
    > 95% as analyzed by SDS-PAGE


Target Background SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as 2019-nCoV (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold to severe diseases. SARS-CoV-2 Spike Protein is composed of S1 domain and S2 domain. The E484K Spike mutation is of significant concern as it has been identified not only in three of the global variants, but also in the newly described American variants. It has been observed in vitro that this mutation alters the shape of the proteins in the viral spike which can potentially mask the antigenic portion from antibodies. There has been much speculation as whether this mutation may impact the effectiveness of monoclonal antibody treatments and cause reinfection in some patients.
Synonyms SARS-CoV-2 S1 protein, E484K; 2019-nCoV S1 protein, E484K

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.